Small and medium enterprises (SMEs) are often the driving force driving the economy of the countries, however, are not always fully exploit its innovative and creative capacity because many of these companies do not know the tools for today gives us the technology, worse the benefits we provide social networks. The aim of this article is intended to discuss best practices in the use of social networks as strategic marketing communication in SMEs. The methodology used in the research is based on the analysis of the state of science, exploratory study on the use of social networks and case studies of success. As a result there are two contributions to the enrichment of scientific literature on the subject: i) identification of best practices in the use of social networks and, ii) social networking as a marketing strategy for SMEs.