This work develops an intelligent tool based on fuzzy cognitive maps to supervisory process control. Fuzzy cognitive maps are a neuro-fuzzy methodology that can accurate model complexly system using a causal-effect fuzzy reasoning. In the proposed approach, new types of concept and relation, not restricted to cause–effect ones, are added to the model resulting in a dynamic fuzzy cognitive map (D-FCM). In this sense, a supervisory system is developed in order to control a fermentation process. This process has a non-linear behavior and presents several problems, such as non-minimum phase and large accommodation time. The supervisor goal is to operate the process in normal and critical conditions. The expert knowledge about the process behavior in both conditions is used to build the D-FCM supervisor. Simulation results are presented in order to validate the proposed intelligent supervisor