ADDIS: A decision support system for evidence-based medicine

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ADDIS: A decision support system for evidence-based medicine
Abstract: Clinical trials are the main source of information for the efficacy and safety evaluation of medical treatments. Although they are of pivotal importance in evidence-based medicine, there is a lack of usable information systems providing data-analysis and decision support capabilities for aggregate clinical trial results. This is partly caused by unavailability (i) of trial data in a structured format suitable for re-analysis, and (ii) of a complete data model for aggregate leve results. In this paper, we develop a unifying data model that enables the development of evidence-based decision support in the absence of a complete data model. We describe the supported decision processes and show how these are implemented in the open source ADDIS software. ADDIS enables semi-automated construction of meta-analyses, network meta-analyses and benefit–risk decision models, and provides visualization of all results
Keywords:	Evidence-based medicine Evidence synthesis Data model Clinical trial Decision analysis
Author(s):	.
Source:	Decision Support Systems 55 (2013) 459–475
Subject:	تصمیم گیری
Category:	مقاله مجله
Release Date:	2013
No of Pages:	17
Price(Tomans):	0
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